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Mouse Anti Human Thymine-DNA G

lycosylase
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  • ￥1080 - 7500
  • Prospecbio
  • 以色列
  • ant-469
  • 2025年07月16日
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    上海经科化学科技有限公司
    16 年钻石会员

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    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      TDG

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      5ug/20ug/100ug

    规格：5ug产品价格：￥1080.0
    规格：20ug产品价格：￥2415.0
    规格：100ug产品价格：￥7500.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-469

    SYNONYMS

    Thymine-DNA Glycosylase, G/T Mismatch-Specific Thymine DNA Glycosylase, EC 3.2.2.29.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    Thymine-DNA glycosylase (TDG) is a member of the TDG/mug DNA glycosylase family.
    TDG is a nuclear protein that fixes G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. In addition, TDG removes uracil and 5-bromouracil from mispairings with guanine. The TDG enzyme has an essential role in cellular defense against genetic mutation triggered by the spontaneous deamination of 5-methylcytosine and cytosine.

    CLONE

    PAT2F7A.

    PHYSICAL APPEARANCE

    Sterile filtered colorless solution.

    IMMUNOGEN

    Anti-human TDG mAb, clone PAT2F7A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TDG protein 1-410 amino acids purified from E. coli.

    IG SUBCLASS

    Mouse IgG1 heavy chain and Kappa light chain.

    FORMULATION

    1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

    STORAGE PROCEDURES

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

    STABILITY / SHELF LIFE

    12 months at -20°C. 1 month at 4°C.

    APPLICATIONS

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:250.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Thymine-DNA glycosylase (TDG) is a member of the TDG/mug DNA glycosylase family.
    TDG is a nuclear protein that fixes G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. 

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    文献支持
    Mouse Anti Human Thymine-DNA Glycosylase
    ￥1080 - 7500