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Mouse Anti Human Vimentin Biot

inylated
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  • ￥5800 - 8100
  • Prospecbio
  • 以色列
  • ant-246
  • 2025年07月18日
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    上海经科化学科技有限公司
    15 年钻石会员

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    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      Vimentin Biotin

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      0.5mg/1mg

    规格：0.5mg产品价格：￥5800.0
    规格：1mg产品价格：￥8100.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-246

    TYPE

    Mouse Anti Human Monoclonal Antibody.

    INTRODUCTION

    Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.

    CLONE

    hVimentin.

    IMMUNOGEN

    Purified Human Vimentin.

    IG SUBCLASS

    mouse IgG1.

    PURIFICATION METHOD

    Ion exchange column.

    FORMULATION

    1mg/ml in PBS (after reconstitution).

    SHIPPING CONDITIONS

    Antibody is shipped lyophilized at ambient temperature.

    STORAGE PROCEDURES

    In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

    SOLUBILITY

    Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

    TITER

    For intra-cellular staining, use 5-10µl/1,000,000 cells. Wash twice with PBS/Azide before adding the appropriate amount of secondary fluorescent reagent.

    CROSS REACTIVITY

    Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

    APPLICATIONS

    Immunohistochemistry.

    AVAILABLE CONJUGATES

    This antibody is also available conjugated to FITC and non conjugate form.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. 

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    文献支持
    Mouse Anti Human Vimentin Biotinylated
    ￥5800 - 8100