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Hamster Anti Mouse CTLA-4 (CD

152)
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  • ¥4830 - 7100
  • Prospecbio
  • 以色列
  • ant-116
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      CTLA-4

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      0.5mg/1mg

    规格:0.5mg产品价格:¥4830.0
    规格:1mg产品价格:¥7100.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-116

    SYNONYMS

    GSE, CD152, IDDM12, CELIAC3, CTLA-4.

    TYPE

    Hamster Anti Mouse Monoclonal.

    INTRODUCTION

    CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    CLONE

    RYNmCTLA-4.

    IMMUNOGEN

    mixture of mouse activated T cells.

    IG SUBCLASS

    Hamster IgG.

    PURIFICATION METHOD

    Ion exchange column.

    FORMULATION

    1mg/ml in PBS (after reconstitution).

    STORAGE PROCEDURES

    Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

    SOLUBILITY

    Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

    APPLICATIONS

    Blocking and staining antibody. For staining, use for blocking CTLA-4 function should be determined by the investigator.

    AVAILABLE CONJUGATES

    This antibody is only available as purified antibody.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    相关实验
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    文献支持
    Hamster Anti Mouse CTLA-4 (CD152)
    ¥4830 - 7100