Mouse Anti Human CD3E
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Mouse Anti Human CD3E

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  • ¥1080 - 7500
  • Prospecbio
  • 以色列
  • ant-557
  • 2025年07月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      CD3E

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/20ug/100ug

    规格:5ug产品价格:¥1080.0
    规格:20ug产品价格:¥2415.0
    规格:100ug产品价格:¥7500.0

    Mouse Anti Human CD3E

    CATALOGUE NUMBER

    ANT-557

    SYNONYMS

    T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, T3E, TCRE.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    CD3-epsilonpolypeptide (CD3E) along with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. This complex has an imperative role in coupling antigen recognition to a number of intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are found in the same cluster on chromosome 11. The epsilon polypeptide plays a vital role in T-cell development. CD3E gene defects cause immunodeficiency. CD3E is also linked to a susceptibility to type I diabetes in women.

    CLONE

    PAT3H3AT.

    PHYSICAL APPEARANCE

    Sterile filtered colorless solution.

    IMMUNOGEN

    Anti-human CD3E mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD3E protein 23-126 amino acids purified from E. coli.

    IG SUBCLASS

    Mouse IgG1 heavy chain and k light chain.

    PURIFICATION METHOD

    CD3E antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.

    FORMULATION

    1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

    STORAGE PROCEDURES

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. 
    Prevent freeze thaw cycles.

    STABILITY / SHELF LIFE

    12 months at -20°C. 1 month at 4°C.

    APPLICATIONS

    CD3E antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    CD3-epsilonpolypeptide (CD3E) along with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. This complex has an imperative role in coupling antigen recognition to a number of intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are found in the same cluster on chromosome 11. The epsilon polypeptide plays a vital role in T-cell development. CD3E gene defects cause immunodeficiency. CD3E is also linked to a susceptibility to type I diabetes in women.

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    文献支持
    Mouse Anti Human CD3E
    ¥1080 - 7500