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Mouse Anti Human Tumor Necrosi

s Factor-alpha
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  • ¥4830 - 7100
  • Prospecbio
  • 以色列
  • ant-124
  • 2025年07月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      TNFA

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      0.5mg/1mg

    规格:0.5mg产品价格:¥4830.0
    规格:1mg产品价格:¥7100.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-124

    SYNONYMS

    TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.
    TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.
    Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.

    CLONE

    NYRhTNFa-E2.

    IMMUNOGEN

    r.Human TNF-a.

    IG SUBCLASS

    Mouse IgG1.

    PURIFICATION METHOD

    ion exchange.

    FORMULATION

    1mg/ml in PBS (after reconstitution).

    SHIPPING CONDITIONS

    Antibody is shipped lyophilized at ambient temperature.

    STORAGE PROCEDURES

    In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

    SOLUBILITY

    Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

    TITER

    In direct ELISA, using alkaline phosphatase goat anti-mouse Ig (Jackson Laboratories) 1:10,000 dilution will yield 0.7 O.D within 10 minutes.

    APPLICATIONS

    Direct ELISA, Western Blot, Immuneprecipitation, Intracellular staining.

    NOTE

    This antibody will bind very well to protein A in a buffer (PBS) containing high salt concentration (3M Nacl).

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.

    相关实验
    • Tumor Necrosis Factor as a Pharmacological Target

      Tumor necrosis factor (TNF) was originally described as a molecule with antitumor properties released by macrophages stimulated with bacterial products. Almost at the same time that TNF was cloned, it was found to be identical to cachectin

    • Typing of Tumor Necrosis Factor Alleles

      The tumor necrosis factor (TNF) locus contains the three closely related cytokine genes: TNF , and lymphotoxin α and �. The gene cluster lies at the telomeric end of the class III region of the major histocompatibility complex (MHC

    • Assay of Soluble Tumor Necrosis Factor Receptors

      Over the last decade, numerous basic biological as well as experimental and clinical studies have firmly established the significance of tumor necrosis factor (TNF) as a principal proximal mediator of sepsis (1 –

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    文献支持
    Mouse Anti Human Tumor Necrosis Factor-alpha
    ¥4830 - 7100