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Recombinant Human Nucleopurin

62kDa
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  • ¥1080 - 61000
  • Prospecbio
  • 以色列
  • pro-999
  • 2025年07月08日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      NUP62

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/20ug/1mg

    规格:5ug产品价格:¥1080.0
    规格:20ug产品价格:¥2415.0
    规格:1mg产品价格:¥61000.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-999

    SYNONYMS

    Nuclear pore glycoprotein p62, 62 kDa nucleoporin, Nucleoporin Nup62, NUP62, p62, IBSN, SNDI.

    INTRODUCTION

    Nucleopurin 62kDa (NUP62) belongs to the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. Nucleoporins are the principal components of the nuclear pore complex in eukaryotic cells. This complex is a colossal structure which extends across the nuclear envelope, forming an entryway that regulates the stream of macromolecules between the nucleus and the cytoplasm. NUP62 associates with the importin alpha/beta complex that is involved in the import of proteins containing nuclear localization signals. Defects in the NUP62 are the cause of SNDI (infantile striatonigral degeneration), aka infantile bilateral striatal necrosis (IBSN) or familial striatal degeneration.

    DESCRIPTION

    NUP62 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 66 kDa.

    NUP62 is expressed with a -10x His tag at N-terminus and purified by proprietary chromatographic techniques.

    SOURCE

    Sf9 insect cells.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    NUP62 is supplied in 20mM HEPES buffer pH-8, 200mM NaCl and 20% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 95% as determined by SDS-PAGE.

    COATING CONCENTRATION

    0.5-1.0 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.

    APPLICATIONS

    Western blot with Polyclonal anti-Nup62 antibodies.

    IMMUNOLOGICAL FUNCTIONS

    1. Binds IgG-type human auto-antibodies.
    2. Standard ELISA test (checker-board analysis of positive/negative sera), immunodot analysis with positive/negative samples.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     

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    图标文献和实验
    该产品被引用文献

    NUP62 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 66 kDa.

    NUP62 is expressed with a -10x His tag at N-terminus and purified by proprietary chromatographic techniques.

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    文献支持
    Recombinant Human Nucleopurin 62kDa
    ¥1080 - 61000