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Recombinant Human NFKB Inhibit

or Interacting Ras-Like 2
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  • ￥1080 - 87906
  • Prospecbio
  • 以色列
  • pro-1091
  • 2025年07月16日
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    上海经科化学科技有限公司
    16 年钻石会员

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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      NKIRAS2

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      2ug/10ug/1mg

    规格：2ug产品价格：￥1080.0
    规格：10ug产品价格：￥2415.0
    规格：1mg产品价格：￥87906.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1091

    SYNONYMS

    NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2, NKIRAS2, KBRAS2.

    INTRODUCTION

    NFKB inhibitor interacting Ras-like 2 (NKIRAS2) is an inhibitor of the transcription factor NF-kappaB. NKIRAS2 is similar to the Ras-like small GTPases which associate with IkappaB. The Ras-like proteins- NKIRAS1 and NKIRAS2, interact with the PEST domains of I?B? and I?B? and reduce their rate of degradation. NKIRAS2 is an atypical Ras-like protein which functions as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more impervious to degradation.

    DESCRIPTION

    NKIRAS2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 215 amino acids (1-191 a.a) and having a molecular mass of 24kDa.
    NKIRAS2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered colorless solution.

    FORMULATION

    NKIRAS2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 90.0% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.S.SHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRS
    LLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     

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    图标文献和实验
    该产品被引用文献

    NKIRAS2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 215 amino acids (1-191 a.a) and having a molecular mass of 24kDa.
    NKIRAS2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    相关实验

    • Ribonuclease A (RNase A), DNase-free

      in transcribed genes: Amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells, Proc. Natl. Acad. Sci. USA, 82, 7575-7579, 1985. 7.Sela, M., Anfinsen, C.B., Some spectrophotometric and polarimetric experiments with ribonuclease

    • 白介素2的信号通路图

      after specifically interacting with its receptors. Human IL-2 is a 133-amino acid polypeptide with a molecular mass of 15-18 kDa. IL-2 signaling is mediated by a multichain receptor complex consisting of an alpha (CD25), beta (CD122), and gamma (CD132) chain. The IL

    • [资源] 所有的看家基因(housekeeping genes)列表+引物设计服务

      from the article "Human Housekeeping genes are compact," published in Trends in Genetics 19, 362-365 (2003). Each gene name/description is followed by its geometric average expression level according to the data published by Su et al. Genes designated by asterisk

    查看更多相关实验 >

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    文献支持
    Recombinant Human NFKB Inhibitor Interacting Ras-Like 2
    ￥1080 - 87906