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Recombinant Human Nucleic Acid

Binding Protein 1
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  • ￥1080 - 45885
  • Prospecbio
  • 以色列
  • pro-1718
  • 2025年07月13日
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    上海经科化学科技有限公司
    15 年钻石会员

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    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      NABP1

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      5ug/20ug/1mg

    规格：5ug产品价格：￥1080.0
    规格：20ug产品价格：￥2415.0
    规格：1mg产品价格：￥45885.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1718

    SYNONYMS

    Nucleic Acid Binding Protein 1, OBFC2A, Sensor Of Single-Strand DNA Complex Subunit B2, Single-Stranded DNA-Binding Protein 2, SSB2, Oligonucleotide/Oligosaccharide-Binding Fold Containing 2A, Nucleic Acid-Binding Protein 1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 2A, Sensor Of SsDNA Subunit B2, SOSS-B2, SOSS Complex Subunit B2, hSSB2.

    INTRODUCTION

    Nucleic acid binding protein 1 is a part of the SOSS complex, a multiprotein complex which functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, NABP1 acts as a sensor of single-stranded DNA which binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex links with DNA lesions and affects diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. NABP1 is essential for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

    DESCRIPTION

    NABP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and having a molecular mass of 24.8kDa.
    NABP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    NABP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) 0.2M, NaCl, 50% glycerol and 2mM DTT.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 95.0% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.S.SHHHHHH SSGLVPRGSH MGSMNRVNDP LIFIRDIKPG LKNLNVVFIV LEIGRVTKTK DGHEVRSCKV ADKTGSITIS VWDEIGGLIQ PGDIIRLTRG YASMWKGCLT LYTGRGGELQ KIGEFCMVYS EVPNFSEPNP DYRGQQNKGA QSEQKNNSMN SNMGTGTFGP VGNGVHTGPE SREHQFSHAG RSNGRGLINP QLQGTASNQT VMTTISNGRD PRRAFKR.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献
    NABP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and having a molecular mass of 24.8kDa.
    NABP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
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    Recombinant Human Nucleic Acid Binding Protein 1
    ￥1080 - 45885