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- pro-745
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
for future use below -18°C
- 保质期：
See instructions
- 英文名：
MSH6
- 库存：
常规产品有备货
- 供应商：
上海经科化学科技有限公司
- CAS号：
无
- 规格：
2ug/5ug/10ug
| 规格： | 2ug | 产品价格： | ￥3381.0 |
|---|---|---|---|
| 规格： | 5ug | 产品价格： | ￥5000.0 |
| 规格： | 10ug | 产品价格： | ￥8800.0 |
CATALOGUE NUMBER
PRO-745
SYNONYMS
INTRODUCTION
MSH6 deficiency result in hereditary non-polyposis colorectal cancer (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease linked with rise in cancer susceptibility. MSH6 is is known by its familial predisposition to premature onset colorectal carcinoma (crc).
MSH6 is involved in repairing DNA. MSH6 protein repairs mistakes that occure during DNA replication in preparation for cell division. The MSH6 protein bonds with MSH2 protein and form an active protein complex which recognizes specific parts on the DNA where mistakes have been made during DNA replication. MLH1-PMS2 protein complex, afterwards takes over with the repair. MSH6 gene is part of the set of the mismatch repair (MMR) genes.
DESCRIPTION
SOURCE
PHYSICAL APPEARANCE
FORMULATION
STABILITY
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
SAFETY DATA SHEET
SDS
USAGE
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文献和实验MSH6 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 51 amino acids (350-400 a.a.) having a total Mw of 33 kDa. Human MSH6 is fused to a GST tag and purified by proprietary chromatographic techniques.
Introduction of human 14-3-3 proteins
The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14
High-Level Expression of a Phage Display-Derived scFv in Pichia pastoris
of human colon cancer. The expression and purification of A33scFv was optimized for the methylotrophic yeast P. pastoris . P. pastoris with a MutS phenotype was selected to express A33scFv under regulation of the methanol-inducible AOX1 promoter
Vector systems for cloning different sizes of DNA fragments
clusters or other DNA sequences of interest. However, the size of different DNA sequences of interest can vary enormously (e.g. human gene sizes are known to vary between 0.1 kb and 2.5 Mb). The first cell-based cloning systems to be developed could clone
技术资料