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Recombinant Human MDS1 And EVI

1 Complex Locus
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  • ¥1080 - 20286
  • Prospecbio
  • 以色列
  • pro-1766
  • 2026年01月17日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      MECOM

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      2ug/10ug/100ug

    规格:2ug产品价格:¥1080.0
    规格:10ug产品价格:¥2415.0
    规格:100ug产品价格:¥20286.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1766

    SYNONYMS

    MDS1 And EVI1 Complex Locus, Ecotropic Virus Integration Site 1 Protein Homolog, Myelodysplasia Syndrome-Associated Protein 1, AML1-EVI-1, MDS1-EVI1, EVI1, MDS1, PRDM3, AML1-EVI-1 Fusion Protein, MDS1 And EVI1 Complex Locus Protein EVI1, MDS1 And EVI1 Complex Locus Protein MDS1, Oncogene EVI1, Zinc Finger Protein Evi1.

    INTRODUCTION

    MDS1 is a transcriptional regulator and oncoprotein which takes part in hematopoiesis, development, cell differentiation, apoptosis and proliferation. MDS1 is able to interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. Overexpression, as a result of translocation with the AML1 gene, is known to cause leukemia. A number of transcript variants encoding several different isoforms were found.

    DESCRIPTION

    MECOM Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (1-169 a.a) and having a molecular mass of 21.1kDa.
    MECOM is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    MECOM protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.4M Urea and 10% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please avoid freeze thaw cycles.

    PURITY

    Greater than 85.0% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.S.SHHHHHH SSGLVPRGSH MGSMRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAP IYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献
    MECOM Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (1-169 a.a) and having a molecular mass of 21.1kDa.
    MECOM is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
    相关实验
    • 最新基因组学术语表New Genome Glossary

      at a second locus due to crossing over in a single generation. In human beings, one centimorgan is equivalent, on average, to one million base pairs. Centromere: A specialized chromosome region to which spindle fibers attach during cell division

    • Nucleic acid hybridization assays using cloned DNA probes

      for the presence of related sequences within a complex target of uncloned DNA or RNA. Sometimes the assay is restricted to simply checking for presence or absence of sequences related to the probe. In other cases, useful information can be obtained

    • Mouse Strains and Genetic Nomenclature

      Zou, F., Gelfond, J.A., Airey, D.C., Lu, L., Manly, K.F., Williams, R.W., and Threadgill, D.W. 2005. Quantitative trait locus analysis using recombinant inbred intercrosses: Theoretical and empirical considerations. Genetics 170:1299‐1311

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    文献支持
    Recombinant Human MDS1 And EVI1 Complex Locus
    ¥1080 - 20286