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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
for future use below -18°C
- 保质期:
See instructions
- 英文名:
KLRK1, Sf9
- 库存:
常规产品有备货
- 供应商:
上海经科化学科技有限公司
- CAS号:
无
- 规格:
2ug/10ug/1mg
| 规格: | 2ug | 产品价格: | ¥1080.0 |
|---|---|---|---|
| 规格: | 10ug | 产品价格: | ¥2415.0 |
| 规格: | 1mg | 产品价格: | ¥87906.0 |

CATALOGUE NUMBER
PRO-2474
SYNONYMS
Killer Cell Lectin Like Receptor K1, Killer Cell Lectin-Like Receptor Subfamily K, Member 1, NKG2-D-Activating NK Receptor, NK Cell Receptor D, D12S2489E, NKG2D, DNA Segment On Chromosome 12 (Unique) 2489 Expressed Sequence, Killer Cell Lectin-Like Receptor Subfamily K Member 1, NKG2-D Type II Integral Membrane Protein, CD314 Antigen, NKG2-D, CD314, KLR.
INTRODUCTION
Killer Cell lectin-Like Receptor Subfamily K, Member 1 (KLRK1) is an activating receptor which has recently generated considerable interest. The most fascinating of these, are a couple of closely related proteins known as MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and their genes have elements of heat shock promoters. Thus, MICA and MICB are expressed in the course of cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination has a crucial role in the immune response to various pathologies.
DESCRIPTION
KLRK1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 386 amino acids (73-216a.a.) and having a molecular mass of 43.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).
KLRK1 is expressed with a 242 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
SOURCE
PHYSICAL APPEARANCE
FORMULATION
KLRK1 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
STABILITY
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
PURITY
Greater than 95.0% as determined by SDS-PAGE.
AMINO ACID SEQUENCE
ADPIWSAVFL NSLFNQEVQI PLTESYCGPC PKNWICYKNN CYQFFDESKN WYESQASCMS QNASLLKVYS KEDQDLLKLV KSYHWMGLVH IPTNGSWQWE DGSILSPNLL TIIEMQKGDC ALYASSFKGY IENCSTPNTY ICMQRTVVEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH.
SAFETY DATA SHEET
SDS
USAGE
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文献和实验KLRK1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 386 amino acids (73-216a.a.) and having a molecular mass of 43.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).
KLRK1 is expressed with a 242 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
Introduction of human 14-3-3 proteins
regulation.We report here the crystal structure of the human T-cell 14-3-3 isoform (tau)dimer at 2.6 A resolution.Each monomer (Mr 28K)is composed of an unusual arrangement of nine antiparallel alpha-helices organized as two structural domains.The dimer
【分享】Human press METHODS IN MOLECULAR BIOLOGY
Culture. Edited by Walker, John M.1984 6. Plant Cell and Tissue Culture. Edited by Walker, John M., 1984 7. Gene Transfer and Expression Protocols. Edited by Murray, Edward J., 1992 8. Practical Molecular Virology. Edited by Collins, Mary K., 1992
secreted bioactive cytotoxic lymphocyte maturation factor.PNAS,1991;88:4143 23.Hayashida K,et al.Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor(GM-CSF):reconstitution of a high-affinity
技术资料









