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- pro-1106
- 2026年01月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
for future use below -18°C
- 保质期：
See instructions
- 英文名：
ERCC1
- 库存：
常规产品有备货
- 供应商：
上海经科化学科技有限公司
- CAS号：
无
- 规格：
2ug/10ug/1mg
| 规格： | 2ug | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 10ug | 产品价格： | ￥2415.0 |
| 规格： | 1mg | 产品价格： | ￥87906.0 |
CATALOGUE NUMBER
PRO-1106
SYNONYMS
INTRODUCTION
ERCC1 polypeptide is essential for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which takes part in repair and mitotic intra-chromosomal recombination. NER mechanism includes dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.
DESCRIPTION
ERCC1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
SOURCE
PHYSICAL APPEARANCE
FORMULATION
STABILITY
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
PURITY
AMINO ACID SEQUENCE
SAFETY DATA SHEET
SDS
USAGE
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文献和实验ERCC1 Human Recombinant produced in E. coli is a single polypeptide chain containing 297 amino acids (1-273) and having a molecular mass of 32.5kDa.
ERCC1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Analysis of Alterations in a Base-Excision Repair Gene in Lung Cancer
; Proliferating Cell Nuclear Antigen, PCNA; X-Ray Cross Complementing 1, XRCC1, Xeroderma Pigmentosum, XP; Base-excision repair, BER; Nucleotide excision repair, NER.
Nucleotide Excision Repair Coupled to Chromatin Assembly
The packaging of DNA into a chromatin structure within the eukaryotic nucleus can affect processes such as DNA replication, transcription, recombination and repair. During nucleotide excision repair (NER), a major DNA repair pathway
Nucleotide Excision Repair in Saccharomyces cerevisiae Whole-Cell Extracts
Nucleotide excision repair (NER) is a particularly versatile pathway of DNA repair capable of removing a broad spectrum of DNA lesions in both prokaryotes and eukaryotes (1 –3 ). NER involves steps of damage recognition, incision
技术资料