Recombinant Human Glycolipid T

Ceramide-1-Phosphate Transfer Protein, Glycolipid Transfer Protein Domain-Containing Protein 1, Glycolipid Transfer Protein Domain Containing 1, GLTP Domain-Containing Protein 1, GLTPD1, GLTPD1, Ceramide-1-phosphate transfer protein, CPTP.

Glycolipid Transfer Protein Domain Containing 1 (GLTPD1) belongs to the GLTP family. GLTPD1 mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. GLTPD1 is essential for normal structure of the Golgi stacks. In addition, GLTPD1 is able to bind phosphoceramides with a diversity of aliphatic chains, however GLTPD1 has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains. Moreover, GLTPD1 is inefficient with phosphoceramides which contains lignoceryl (C24:0).  GLTPD1 participates in the regulation of the cellular levels of ceramide-1-phosphate, and in that way contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid.

Escherichia Coli.

Sterile Filtered clear solution.

GLTPD1 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4), 50% glycerol and 1mM DTT.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.

Greater than 90.0% as determined by SDS-PAGE.

MG.S/SHHHHHH SSGLVPRGSH MGSMDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLG TIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHW LQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRA VTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAE HSLLDLP.

SDS

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