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Recombinant Human Centromere P

rotein-B
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  • ¥1080 - 87906
  • Prospecbio
  • 以色列
  • pro-390
  • 2026年01月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      CENPB

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/20ug/1mg

    规格:5ug产品价格:¥1080.0
    规格:20ug产品价格:¥2415.0
    规格:1mg产品价格:¥87906.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-390

    SYNONYMS

    Major centromere autoantigen B, Centromere protein B, CENP-B, CENPB.

    INTRODUCTION

    Centromere proteins are a group of proteins which form and/or mediate the function of centromeres, the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently, 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies, the anti-centromere antibodies.
    CENPB is the most important of the centromeric autoantigens: it has a molecular weight of approx. 66 kDa and plays an important role in the formation of the centromeric chromatin. CENPB antibodies are present in the sera of up to 80% of patients with CREST syndrome.

    DESCRIPTION

    CENPB Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 80kDa.
    CENPB is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.

    SOURCE

    Sf9 insect cells.

    PHYSICAL APPEARANCE

    Sterile Filtered liquid formulation.

    FORMULATION

    CENPB is supplied at a concentration of in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. 
    Store, frozen at -20°C for longer periods of time. 
    Avoid multiple freeze-thaw cycles.

    COATING CONCENTRATION

    0.15-0.375 µg/ml (depending on the type of ELISA plate and coating buffer).
    Suitable for biotinylation and iodination.

    PURITY

    Greater than 95% as determined by SDS-PAGE.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     
     

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    图标文献和实验
    该产品被引用文献

    CENPB Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 80kDa.
    CENPB is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.

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    文献支持
    Recombinant Human Centromere Protein-B
    ¥1080 - 87906