- ￥1080 - 45885
- Prospecbio
- 以色列
- enz-545
- 2026年01月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
for future use below -18°C
- 保质期：
See instructions
- 英文名：
WARS
- 库存：
常规产品有备货
- 供应商：
上海经科化学科技有限公司
- CAS号：
无
- 规格：
5ug/25ug/1mg
| 规格： | 5ug | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 25ug | 产品价格： | ￥2415.0 |
| 规格： | 1mg | 产品价格： | ￥45885.0 |
CATALOGUE NUMBER
ENZ-545
SYNONYMS
GAMMA-2, IFI53, IFP53, WRS, WARS, TrpRS, hWRS, EC=6.1.1.2, Tryptophanyl-tRNA synthetase, INF-induced protein 53, Tryptophan--tRNA ligase, GAMMA-2.
INTRODUCTION
WARS is part of the class I tRNA synthetase family. 2 types of tryptophanyl tRNA synthetase exist, a cytoplasmic form, called WARS, and a mitochondrial form, called WARS2. WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by INF. WARS controls ERK, Akt, and eNOS activation pathways that are related with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
DESCRIPTION
SOURCE
PHYSICAL APPEARANCE
FORMULATION
STABILITY
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
PURITY
AMINO ACID SEQUENCE
SAFETY DATA SHEET
SDS
USAGE
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文献和实验WARS Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 491 amino acids (1-471 a.a.) and having a molecular mass of 55.3 kDa. The WARS is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Methods to Assay Inhibitors of tRNA Synthetase Activity
could be a potential antibacterial agent. Only one aa-RS inhibitor, the Ile-RS inhibitor mupirocin, is currently marketed as an antibacterial agent. We focused on phenylalanyl (Phe)-tRNA synthetase (Phe-RS), but the described methods are not restricted to Phe-RS
酶分类的主要类别之一。为催化与 ATP等三磷酸核苷的分解伴有形成新化学键可逆反应的酶之总称。催化具有有机化学意义的合成反应，分为两个分子相加的裂解酶和移换反应的移换酶两类。所以还是将不伴随腺苷三磷酸的分解而催化合成反应的酶称为合成酶（ Synthase）较为适宜。合成酶催化的反应含 ATP等基质，反应复杂， ATP分解为 ADP与正磷酸或 AMP与焦磷酸。根据生成键的种类而更分为：（ 1） C-O键，例如氨酰 tRNA合成酶；（ 2） C-S键，例如乙酰 CoA合成
A variety of in vivo selection and screening methods have been developed for the directed evolution of protein function. Typically, in vivo selection strategies involve the identification of new binding or catalytic functions based
技术资料