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- enz-1068
- 2026年01月03日
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- 文献和实验
- 技术资料
- 保存条件：
for future use below -18°C
- 保质期：
See instructions
- 英文名：
mMDH2
- 库存：
常规产品有备货
- 供应商：
上海经科化学科技有限公司
- CAS号：
无
- 规格：
2ug/10ug/1mg
| 规格： | 2ug | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 10ug | 产品价格： | ￥2415.0 |
| 规格： | 1mg | 产品价格： | ￥87906.0 |
CATALOGUE NUMBER
ENZ-1068
SYNONYMS
INTRODUCTION
MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highy expressed in the adrenal system, small intestine, heart and pancreas.
DESCRIPTION
MDH2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 335 amino acids (25-338a.a.) and having a molecular mass of 35.4kDa. MDH2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
SOURCE
PHYSICAL APPEARANCE
FORMULATION
MDH2 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4) and 20% glycerol.
STABILITY
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
AMINO ACID SEQUENCE
MG./S-SHHHHHH SSGLVPRGSH MAKVAVLGAS GGIGQPLSLL LKNSPLVSRL TLYDIAHTPG VAADLSHIET RANVKGYLGP EQLPDCLKGC DVVVIPAGVP RKPGMTRDDL FNTNATIVAT LTAACAQHCP EAMVCIIANP VNSTIPITAE VFKKHGVYNP NKIFGVTTLD IVRANTFVAE LKGLDPARVN VPVIGGHAGK TIIPLISQCT PKVDFPQDQL ATLTGRIQEA GTEVVKAKAG AGSATLSMAY AGARFVFSLV DAMNGKEGVV ECSFVQSKET ECTYFSTPLL LGKKGLEKNL GIGKITPFEE KMIAEAIPEL KASIKKGEDF VKNMK.
PURITY
BIOLOGICAL ACTIVITY
Specific activity is > 800 units/mg, and is defined as the amount of enzyme that cleaves 1umole of oxaloacetate and beta-NADH to Lmalate and beta-NAD per minute at pH8.0 at 37°C.
SAFETY DATA SHEET
SDS
USAGE
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文献和实验MDH2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 335 amino acids (25-338a.a.) and having a molecular mass of 35.4kDa. MDH2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
domains-containing protein 3 (NLRP3), partial CSB-EP822275HU1 NQO1 Recombinant Mouse NAD (P)H dehydrogenase [quinone] 1 (Nqo1) CSB-EP717562MO RASA2 Recombinant Human Ras GTPase-activating protein 2 (RASA2), partial CSB-MP622992HU TSHR
的致病强度差异。进一步RNA测序发现Cbl和SF1为关键下游效应分子，过表达可部分挽救缺陷。此外，研究还鉴定出DMAP1相关的特异性DNA甲基化特征，可作为辅助诊断的分子标志物。该研究将DMAP1纳入神经发育障碍致病基因谱，为理解表观遗传调控相关疾病机制提供了新范式。 推荐产品 靶点 重组蛋白 货号 ALDH1B1 Recombinant Human Aldehyde dehydrogenase X, mitochondrial (ALDH
potassium channel 2 (KCNJ2), partial CSB-MP012055HU1 MINDY2 Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase MINDY-2 (Mindy2) CSB-EP750855MO PHGDH Recombinant Human D-3-phosphoglycerate dehydrogenase (PHGDH), partial CSB-EP017920HU
技术资料
