产品封面图
文献支持

Recombinant Human Hydroxymethy

lbilane Synthase
收藏
  • ￥1080 - 45885
  • Prospecbio
  • 以色列
  • enz-581
  • 2026年01月03日
    avatar
    上海经科化学科技有限公司
    16 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      HMBS

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      5ug/20ug/1mg

    规格：5ug产品价格：￥1080.0
    规格：20ug产品价格：￥2415.0
    规格：1mg产品价格：￥45885.0

     

    CATALOGUE NUMBER

    ENZ-581

    SYNONYMS

    Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase, HMBS, PBGD, UPS, PORC.

    INTRODUCTION

    Porphobilinogen deaminase (HMBS) belongs to the hydroxymethylbilane synthase superfamily. HMBS is a cytoplasmic enzyme found in the heme synthesis pathway. HMBS is the 3rd enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of 4 porphobilinogen molecules into the linear hydroxymethylbilane. HMBS gene mutations cause errors in pyrrole metabolism which in turn lead to the autosomal dominant disease acute intermittent porphyria.

    DESCRIPTION

    HMBS Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids (1-361) and having a molecular mass of 41.9kDa.
    HMBS is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered colorless solution.

    FORMULATION

    The HMBS solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 95.0% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.-S/SHHHHHH SSGLVPRGSH MGSHMSGNGN AAATAEENSP KMRVIRVGTR KSQLARIQTD SVVATLKASY PGLQFEIIAM STTGDKILDT ALSKIGEKSL FTKELEHALE KNEVDLVVHS LKDLPTVLPP GFTIGAICKR ENPHDAVVFH PKFVGKTLET LPEKSVVGTS SLRRAAQLQR
    KFPHLEFRSI RGNLNTRLRK LDEQQEFSAI ILATAGLQRM GWHNRVGQIL HPEECMYAVG QGALGVEVRA KDQDILDLVG VLHDPETLLR CIAERAFLRH LEGGCSVPVA VHTAMKDGQL YLTGGVWSLD GSDSIQETMQ ATIHVPAQHE DGPEDDPQLV GITARNIPRG PQLAAQNLGI
    SLANLLLSKG AKNILDVARQ LNDAH.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    HMBS Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids (1-361) and having a molecular mass of 41.9kDa.
    HMBS is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    相关实验

    • Construction of Recombinant Human Cytomegalovirus

      The use of reverse genetics to generate recombinant viruses allows the researcher to investigate the exact functional significance of particular viral genes during the virus life cycle, by means of their deletion or modification in the viral

    • Immunochemical Detection of Nitric Oxide Synthase in Human Tissue

      To date three distinct isoforms of nitric oxide synthase (NOS) have been identified. Two isoforms are considered to be expressed constitutively—neu-ronal NOS (nNOS; type I NOS) and endothelial NOS (eNOS; type III NOS). The third isoform

    • Cloning and Expression of Human Inducible Nitric Oxide Synthase

      NO synthase (NOS) pathway was first characterized and cloned in murine macrophages (1 –3 ). Activation with lipopolysaccharide (LPS) and interferon-γ (IFN-γ) was uniformly used in these studies to increase inducible (i) NOS expression and improve cloning

    查看更多相关实验 >

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Recombinant Human Hydroxymethylbilane Synthase (HMBS)
    询价
    默瑞（上海）生物科技有限公司
    2025年07月10日询价
    Human Hydroxymethylbilane Synthase (HMBS) ELISA Kit
    ￥3377
    广州威佳科技有限公司
    2025年06月04日询价
    Recombinant Human Citrate Synthase
    ￥1080
    上海经科化学科技有限公司
    2026年01月01日询价
    Recombinant Human Deoxyhypusine synthase/DHS
    ￥11827
    上海吉至生化科技有限公司
    2025年07月11日询价
    Prostaglandin F Synthase (human recombinant)
    ￥5320
    北京孚博生物科技有限公司
    2026年01月20日询价
    文献支持
    Recombinant Human Hydroxymethylbilane Synthase
    ￥1080 - 45885