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Human Growth Hormone Releasing

Hormone
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  • ¥1080 - 7100
  • Prospecbio
  • 以色列
  • hor-235
  • 2025年12月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      GHRH

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      250ug/1mg/5mg

    规格:250ug产品价格:¥1080.0
    规格:1mg产品价格:¥2415.0
    规格:5mg产品价格:¥7100.0

     

    CATALOGUE NUMBER

    HOR-235

    SYNONYMS

    Somatoliberin, Growth hormone-releasing factor, GRF, Growth hormone-releasing hormone, GHRH, Somatocrinin, Somatorelin, Sermorelin, GHRF, MGC119781.

    INTRODUCTION

    Growth-hormone-releasing hormone (GHRH), also known as growth-hormone-releasing factor (GRF or GHRF) or somatocrinin, is a 44-amino acidpeptide hormoneproduced in the arcuate nucleusof the hypothalamus.
    GHRH is released from neurosecretory nerve terminals of these arcuate neurons, and is carried by the hypothalamo-hypophysial portal circulation to the anterior pituitary glandwhere it stimulates growth hormone(GH) secretion. GHRH also stimulates the production of GH. GHRH is released in a pulsatile manner, stimulating similar pulsatile release of GH. In addition, GHRH also promotes slow-wave sleepdirectly.

    DESCRIPTION

    Growth Hormone Releasing Hormone Human Synthetic is a single, non-glycosylated, polypeptide chain containing 29 amino acids and having a molecular mass of 3358.9 Dalton.
    Corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone consisting of 44 amino acid residues.
    The GHRH is purified by proprietary chromatographic techniques.

    PHYSICAL APPEARANCE

    Sterile Filtered White lyophilized (freeze-dried) powder.

    FORMULATION

    The GHRH peptide (1mg/ml) was lyophilized after extensive dialyses against 1.7 mg sodium phosphate buffer (0.1 mg sodium phosphate monobasic & 1.6 mg sodium phosphate dibasic).

    SOLUBILITY

    It is recommended to reconstitute the lyophilized GHRH in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. The GHRH is also soluble in 1% Acetic acid at a concentration of >1mg/ml to give a clear, colorless solution.

    STABILITY

    Lyophilized Growth Hormone Releasing Hormone although stable at room temperature for 3 weeks, should be stored desiccated below
    -18°C. Upon reconstitution GHRF should be stored at 4°C between
    2-7 days and for future use below -18°C.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.

    PURITY

    Greater than 98.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    The free base of sermorelin has the empirical formula C149H24644O42S.
    Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2.

    BIOLOGICAL ACTIVITY

    GHRH increases plasma growth hormone concentrations by directly stimulating the anterior pituitary gland to release natural human growth hormone.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Growth Hormone Releasing Hormone Human Synthetic is a single, non-glycosylated, polypeptide chain containing 29 amino acids and having a molecular mass of 3358.9 Dalton.
    Corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone consisting of 44 amino acid residues.
    The GHRH is purified by proprietary chromatographic techniques.

    相关实验
    • RAT/MOUSE GROWTH HORMONE ELISA KIT

      实验原理 This assay is a Sandwich ELISA based, sequentially, on: 1) capture of rat or mouse Growth Hormone molecules from samples to the wells of a microtiter plate coated by a pre-titered amount of anti-Growth Hormone

    • 生长素 growth hormone,somatotropichormone,somatottopin

         简写STH或GH。脑垂体前叶激素之一。是由前叶特定的细胞(嗜酸性细胞)合成、分泌的。具有促进全身特别是促进长骨生长的作用。但其作用并不相同,随着发生阶段和组织的不同,而有各种变化。为了促进发育完全还需要甲状腺激素的协同作用。如果自小儿期起脑垂体前叶产生生长素的细胞机能异常亢进,则将形成巨人症;如果机能亢进发生在骨端软骨线闭锁以后,则将形成肢端肥大症。生长素能抑制组织中氨基酸的分解,促进氨基酸合成蛋白质,从而使机体的含氮量增加,尿中总氮量减少。生长素的分泌受丘脑下部生长素释放

    • Using High-Content Microscopy to Study Gonadotrophin-Releasing Hormone Regulation of ERK

      Gonadotrophin-releasing hormone (GnRH) is a hypothalamic peptide that acts via Gq/11 -coupled 7TM receptors on pituitary gonadotrophs and mediates the central control of reproduction. Recent evidence also indicates that GnRH can affect

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    文献支持
    Human Growth Hormone Releasing Hormone
    ¥1080 - 7100