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Human Platelet Factor-4 (CXCL4

)
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  • ￥1080 - 48300
  • Prospecbio
  • 以色列
  • chm-234
  • 2025年12月28日
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    上海经科化学科技有限公司
    16 年钻石会员

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    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      PF4

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      5ug/20ug/1mg

    规格：5ug产品价格：￥1080.0
    规格：20ug产品价格：￥2415.0
    规格：1mg产品价格：￥48300.0

     

    CATALOGUE NUMBER

    CHM-234

    SYNONYMS

    CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.

    INTRODUCTION

    Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.

    DESCRIPTION

    Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues.

    SOURCE

    Human Platelets.

    PHYSICAL APPEARANCE

    Sterile Filtered white lyophilized powder.

    FORMULATION

    The CXCL4 protein was lyophilized in PBS buffer pH-7.4.

    SOLUBILITY

    It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    STABILITY

    Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C.
    Please prevent freeze-thaw cycles.

    PURITY

    Greater than 95.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    The sequence of the first four N-terminal amino acids was determined and was found to be Glu-Ala-Glu-Glu.

    ACTIVITY CONTROL

    Binding of HIT-antibodies.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    该产品被引用文献

    Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues.

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    文献支持
    Human Platelet Factor-4 (CXCL4)
    ￥1080 - 48300