产品封面图
文献支持

Recombinant Human Macrophage I

nflammatory protein-1 beta (CCL4)
收藏
  • ￥1080 - 45885
  • Prospecbio
  • 以色列
  • chm-276
  • 2025年12月29日
    avatar
    上海经科化学科技有限公司
    16 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      MIP 1b

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      2ug/10ug/1mg

    规格：2ug产品价格：￥1080.0
    规格：10ug产品价格：￥2415.0
    规格：1mg产品价格：￥45885.0

     

    CATALOGUE NUMBER

    CHM-276

    SYNONYMS

    Small inducible cytokine A4, CCL4, Macrophage inflammatory protein 1-beta, MIP-1- beta, MIP-1-beta(1-69), T-cell activation protein 2, ACT-2, PAT 744, H400, SIS-gamma, Lymphocyte activation gene 1 protein, LAG-1, HC21, G-26 T-lymphocyte-secreted protein, chemokine (C-C motif) ligand 4, ACT2, G-26, LAG1, MIP1B, SCYA4, AT744.1, MGC104418, MGC126025, MGC126026.

    INTRODUCTION

    Macrophage Inflammatory Proteins belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now also named CCL3 and CCL4. Both factors are produced by macrophages after they are stimulated with bacterial endotoxins. MIP-1a and MIP-1b activate human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. MIP-1a and MIP-1b induce synthesis and release of other pro-inflammatory cytokines such as interleukin-1 (IL-1), IL-6 and TNF-alpha from fibroblasts and macrophages. CCL3 and CCL4 genes are both located on human chromosome 17.

    DESCRIPTION

    Macrophage Inflammatory Protein-1 beta Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7620 Dalton.
    The CCL4 is purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered White lyophilized (freeze-dried) powder.

    FORMULATION

    Lyophilized from a concentrated (1mg/ml) solution in water containing no additives.

    SOLUBILITY

    It is recommended to reconstitute the lyophilized Macrophage Inflammatory Protein-1b in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    STABILITY

    Lyophilized MIP-1b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.

    PURITY

    Greater than 99.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    The sequence of the first five N-terminal amino acids was determined and was found to be, Ala-Pro-Met-Gly-Ser.

    BIOLOGICAL ACTIVITY

    The Activity is calculated by the ability to chemoattract Human blood monocytes using a concentration of 5-20ng/ml corresponding to a Specific Activity of 50,000-200,000IU/mg.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    Title: CONFUSION BETWEEN CCL4 AND CCL4L1: AN EXAMPLE TO 
    BEAR IN MIND WHEN USING THIRD-PARTY REAGENTS.

    Publication: Inmunologia Vol. 26 / Num 1/ Enero-Marzo 2007: 51-54 (Spanish).
     
    相关实验
    查看更多相关实验 >

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Recombinant Rat Macrophage Inflammatory protein-1 beta (CCL4)
    ￥1080
    上海经科化学科技有限公司
    2025年12月29日询价
    Recombinant Human Macrophage Inflammatory Protein 3 Beta (MIP3b)
    询价
    默瑞（上海）生物科技有限公司
    2025年07月11日询价
    Macrophage Inflammatory Protein-5 (human)
    ￥5689
    爱必信(上海)生物科技有限公司
    2025年06月28日询价
    Recombinant Human CCL4/MIP-1 beta Protein
    ￥2680
    上海嵘崴达实业有限公司
    2025年11月12日询价
    Macrophage inflammatory protein 2 (mouse), (recombinant)(20µg)
    ￥3163.50
    杭州囊萤科技有限公司
    2025年07月11日询价
    文献支持
    Recombinant Human Macrophage Inflammatory protein-1 beta (CCL4)
    ￥1080 - 45885