- ￥660 - 2640
- Elabscience
- E-AB-F1133C
- 武汉
- 2026年03月25日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
FITC Anti-Human CD274/PD-L1 Antibody流式抗体[29E.2A3]_货号:E-AB-F1133C
- 抗体英文名：
FITC Anti-Human CD274/PD-L1 Antibody[29E.2A3]_货号:E-AB-F1133C
- 靶点：
PD-L1
- 浓度：
5 μL/Test
- 应用范围：
FCM
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
12个月
- 级别：
科研
- 库存：
99
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
FITC
- 克隆性：
Monoclonal
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 形态：
液体
- 亚型：
Mouse IgG2b, κ
- 规格：
100Tests/20Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥1740.0 |
|---|---|---|---|
| 规格： | 20Tests | 产品价格： | ￥660.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥2640.0 |
货号：E-AB-F1133C
| Background |
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
|
| Alternate Names |
B7-H1; PD-L1;Programmed cell death ligand 1;B7 homolog 1;B7-H; B7H1; PDL1; PDCD1L1; PDCD1LG1;
|
| Swissprot |
Q9NZQ7
|
| Gene ID |
29126
|
| Clone No |
29E.2A3
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Application |
FCM
|
| Isotype |
Mouse IgG2b, κ
|
| Isotype Control |
FITC Mouse IgG2b, κ Isotype Control[MPC-11]
|
| Conjugation |
FITC
|
| Conjugation Information |
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验Cuproptosis in microsatellite stable colon cancer cells affects the cytotoxicity of CD8+T through the WNT signaling pathway
IF:4.7
Journal:CHEMICO-BIOLOGICAL INTERACTIONS
DOI:10.1016/j.cbi.2024.111239
Phycoerythrin conjugation protocol
and Centricon concentrators. Add 0.5% sodium azide. Store at 4 °C protected from light. Do not freeze. Figure 1. Analysis of column eluate fractions from PE conjugation of monoclonal antibody IB4 (murine IgG2a, anti-human CD
Anti-GFP/BrdU In Situ Immunostaining
of 2 N HCl x30'. Wash 3x in PBS. Block in 1 mL 10% Horse serum, x30' at room temp. Wash 1x in PBS. Add 0.3 mL Biotinylated anti-BrdU (1:300, with 1% horse serum in PBS). Incubate at 4ºC o.n. or 2 hr. at room temp. Wash 3x in PBS.
Phenotype-specific immunodetection of cyclins using 488/630 nm dual laser flow cytometry
/azide and place on ice. Add 2 mls 70% EtOH in glycerol that has been kept at 4°C. Incubate the cells for at least two hours. Wash once with staining buffer and decant. Add the primary anti-cyclin antibody in a volume of 200 µl. Incubate overnight
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