- ￥744 - 2880
- Elabscience
- E-AB-F1110F
- 武汉
- 2026年03月25日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
PerCP Anti-Human CD8a Antibody流式抗体[OKT-8]_货号:E-AB-F1110F
- 抗体英文名：
PerCP Anti-Human CD8a Antibody[OKT-8]_货号:E-AB-F1110F
- 靶点：
CD8
- 浓度：
5 μL/Test
- 应用范围：
FCM
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
12个月
- 级别：
科研
- 库存：
99
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
APC
- 克隆性：
Monoclonal
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 形态：
液体
- 亚型：
Mouse IgG2a, κ
- 规格：
100Tests/20Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥1872.0 |
|---|---|---|---|
| 规格： | 20Tests | 产品价格： | ￥744.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥2880.0 |
货号：E-AB-F1110F
| Background |
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
|
| Alternate Names |
T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
|
| Swissprot |
P01732
|
| Gene ID |
925
|
| Clone No |
OKT-8
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Application |
FCM
|
| Isotype |
Mouse IgG2a, κ
|
| Conjugation |
PerCP
|
| Conjugation Information |
PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验Hypoxia-induced autophagy in pancreatic cancer counteracts the cytotoxicity of CD8+ T cells by inhibiting the expression of MHC-I
IF:5
Journal:GENES AND IMMUNITY
DOI:10.1038/s41435-024-00315-1
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，Calibur各个荧光素之间可以搭配出16种组合。 比如常用的搭配是F I T C( F L 1 )＋P E（F L 2）＋PerCP（FL3）+APC(FL4), 这个搭配组合可以更改成Alex Fluro(FL1)＋PE（FL2）＋PerCP（FL3）+APC(FL4), 或者FITC(FL1)＋PE（FL2）＋PerCP（FL3）+Alex Fluro(FL4)，或者FITC(FL1)＋PE（FL2）＋PE-Cy5（FL3）+APC(FL4)等等。总之，在第1原则之下，我们可以随意搭配
/v ）封闭。 Fab 片段 抗体是用木瓜蛋白酶消化 IgG 后得到的。这些抗体只含有一个结合位点。它们用来封闭内源性的免疫球蛋白，或者在使用相同物种来源的一抗作多标记的实验中，用于封闭暴露的免疫球蛋白。而二价的抗体（ whole IgG 或 F （ ab’ ） 2 片段）不能用来封闭，因为它们有二个结合位点。封闭后，一些结合位点可能为暴露出来，与一抗结合，从而导致高的背景或假阳性标记。 第二步： 在左边标记“ antibody description ”的拦里找到
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