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- ￥384 - 1032
- Elabscience
- 湖北武汉
- E-AB-F1081J
- 2026年05月28日
- FCM
- Rat
- Human;Mouse
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- 亚型：
Rat IgG2b, κ
- 形态：
液体
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 克隆性：
Monoclonal
- 标记物：
PerCP/Cyanine5.5
- 适应物种：
Human;Mouse
- 保质期：
12个月
- 目录编号：
E-AB-F1081J
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Rat
- 应用范围：
FCM
- 抗体英文名：
PerCP/Cyanine5.5 Anti-Mouse/Human CD11b Antibody[M1/70]_货号:E-AB-F1081J
- 抗体名：
PerCP/Cyanine5.5 Anti-Mouse/Human CD11b Antibody流式抗体[M1/70]_货号:E-AB-F1081J
- 规格：
100Tests/50Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥684.0 |
|---|---|---|---|
| 规格： | 50Tests | 产品价格： | ￥384.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥1032.0 |
产品名称：PerCP/Cyanine5.5 Anti-Mouse/Human CD11b Antibody[M1/70]
货号：E-AB-F1081J
| Background |
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
|
| Alternate Names |
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
|
| Swissprot |
P05555;P11215;
|
| Gene ID |
16409,3684
|
| Clone No |
M1/70
|
| Host |
Rat
|
| Reactivity |
Human;Mouse
|
| Application |
FCM
|
| Isotype |
Rat IgG2b, κ
|
| Isotype Control |
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
|
| Conjugation |
PerCP/Cyanine5.5
|
| Conjugation Information |
PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验-
Helminth reshapes host gut microbiota and immunoregulation by deploying an antimicrobial program of innate immunity
IF: 12.2Journal： Gut Microbes (2025)DOI：10.1080/19490976.2025.2496447Reactivity：Mouse
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CD11a/CD11b/CD11c 分子 CDlla 常用单克隆抗体或代号：MHM24， 2F12； CRIS―3(LFA―lα链，整合素α1) 主要表达细胞：Leu[A5] 分子质量(kDa)和结构：spl80(整合素α) 功 能：与1CAM-l(CD54)、ICAM-2(CDl02)、ICAM-3(C1350)结合，介导细胞黏附；与JAMl结合，参与白细胞穿过内皮细胞
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CD45、CD64、MerTK、CD11c、MHC II、Siglec-F、CD11b、Gr-1流式抗体染色并使用流式细胞仪检测分析巨噬细胞的功能分型。 从上图可以看出，LPS诱导的急性肺炎小鼠相较于健康对照组小鼠而言，肺泡灌洗液中的巨噬细胞比例降低，从84.58%下降到10.70%；cDC也从6.53%下降到0.41%；嗜酸性粒细胞从1.40%下降到0.46%；而中性粒细胞占Non AM的比例大幅增长，从42.98%上升到96.34%。 这直观地展示了LPS诱导的急性肺损伤模型中，肺泡
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