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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Peptide (C)RLGFLGSNTPHENH, corresponding to amino acid residues 2683-2696 () of rat IP3R2 (Accession : P29995).
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Rat
- 目录编号:
GTX54772
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, IHC-Fr
- 浓度:
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
IP3 Receptor II
- 抗体英文名:
IP3 Receptor II antibody
- 抗体名:
IP3 Receptor II 抗体
- 规格:
50 μl
IHC-Fr analysis of rat spinal cord tissue using GTX54772 IP3 Receptor II antibody.
Panel A : IP3R2 (red) appears in neuronal soma (horizontal arrows) and processes (vertical arrows).
Panel B : Nuclear staining using DAPI as the counterstain (blue).
Panel C : Merged image of A and B.
WB analysis of rat brain membrane (lanes 1 and 3) and RBL cell (lanes 2 and 4) lysates using GTX54772 IP3 Receptor II antibody preincubated with or without immunogen peptide.
Dilution : 1:200
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文献和实验Chen L et al., Cell Res 2017 (PMID:28374748)
IP3受体是一种内质网通道蛋白, 由四个相对分子质量为260kDa的糖蛋白组成的四聚体。四个亚基组成一个跨膜的通道, 每个亚基都有IP3结合的部位, 当3~4个部位被IP3占据时, 受体复合物构象发生改变, 打开离子通道, 储藏在内质网中的Ca2 随即释放,进入胞质溶胶。
Immunohistochemical Detection of Angiotensin II Receptor
for cell-specific localization of receptor expression within tissue. The resolution and sensitivity achieved with IHC is far greater than that obtained with classic autoradiography techniques although antireceptor antibody
The Detection of Antibodies to the Angiotensin II-Type 1 Receptor in Transplantation
The detection of auto-antibodies detection is a major aspect of patient’s immunomonitoring. Antibodies directed against the heart and kidney Angiotensin II type 1 receptor (AT1 R) play a major role in antibody mediated rejection after heart
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