- ￥6000
- GeneTex
- 美国
- GTX45774
- 2025年07月14日
- WB
- Rabbit
- Human, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide corresponding to an Internal region of Human ADC
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Rat
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX45774
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
ADC
- 抗体英文名：
ADC antibody, Internal
- 抗体名：
ADC 抗体, Internal
- 规格：
50 μg
WB analysis of COLO205 cells using GTX45774 ADC antibody at 0.2-1μg/ml.
WB analysis of human cerebral cortex tissue, rat cerebral cortex tissue using GTX45774 ADC antibody at 1:3000.
Lane 1: human cerebral cortex
Lane 2: rat cerebral cortex
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文献和实验AntibodyDrug Conjugate (ADC) Clinical Pipeline: A Review
game, requiring thoughtful combination of antibody, linker, and drugs in the context of a target and a defined cancer indication. Lessons learned from the first-generation antibody–drug conjugate (ADC) and improvement of the technology guided the design
并保留抗炎特性，研究人员开始探索靶向疗法。 抗体药物偶联物（ADC） 抗体药物偶联物 (Antibody-drug conjugates, ADC)，这一新概念的开发，旨在克服单独使用单克隆抗体 (mAb) 的局限性。 ADC 是将单克隆抗体与强效细胞毒性有效载荷通过化学连接子偶联而成。 这种靶向给药方法结合了有效载荷的细胞毒性作用 (有效载荷本身毒性过大，通常无法全身给药) 和 mAb 靶向部分的精准性。 通过限制有效载荷与健康组织的接触
Drug-to-Antibody Ratio (DAR) by UV/Vis Spectroscopy
UV/Vis spectroscopy is a simple and convenient method to determine protein concentrations as well as the average number of drugs that are conjugated to the antibody in an antibody–drug conjugate (ADC). Using the measured absorbances
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