EPOR mouse monoclonal antibody

gene_symbol：EPOR
predicted_size：null
Uniprot ID：P19235
description：EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
immunogen：Human recombinant protein fragment corresponding to amino acids 25-250 of human EPOR (NP_000112) produced in E.coli.
recommended_dilution：WB 1:2000, IHC 1:150
predicted_size：null
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：IHC, WB
reactivities：Human