CTNNB1 mouse monoclonal antibo

gene_symbol：CTNNB1
predicted_size：85.3 kDa
Uniprot ID：P35222
description：CTNNB1 mouse monoclonal antibody, clone OTI12H7 (formerly 12H7)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
immunogen：Full length human recombinant protein of human CTNNB1 (NP_001895) produced in HEK293T cell.
recommended_dilution：WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100
predicted_size：85.3 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：FC, IF, IHC, WB
reactivities：Human, Rat, Monkey, Mouse