- ￥5000
- GeneTex
- 美国
- GTX23200
- 2025年07月10日
- WB, IHC-P, IP, IHC
- Mouse
- Human, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Homogenous suspension of 16 week human fetal brain.
- 亚型：
IgG1
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Rat
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX23200
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Mouse
- 应用范围：
WB, IHC-P, IP, IHC
- 浓度：
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
GTX23200 is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin. It does not bind to pediatric or adult brain.
- 抗体英文名：
L1CAM antibody [UJ127]
- 抗体名：
L1CAM 抗体 [UJ127]
- 规格：
500 μl
GTX23200 at a dilution of 1/1000, staining L1CAM (green; Alexa 488 secondary at 1/2000) on 30m coronal rat brain tissue sections in free floating IHC. Images showing neuron body, cytoplasm and axon labeling: [A] neuron; 40x objective [B] neuron and axons;
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文献和实验Li Y et al., Cancer Cell Int 2010 (PMID:20840789)
Bao S et al., Cancer Res 2008 (PMID:18676824)
Cheng L et al., Biochem Biophys Res Commun 2011 (PMID:21371437)
Cheng L et al., EMBO J 2011 (PMID:21297581)
STM：广州医科大学刘铭/谢茂彬合作发现肝细胞癌的新潜在治疗靶点 Claudin 6
组于 Science Translational Medicine 杂志（STM）在线发表题为 Targeting tumor lineage plasticity in hepatocellular carcinoma using an anti-CLDN6 antibody-drug conjugate 的研究论文。这项研究揭示了细胞紧密连接（tight junction）蛋白 Claudin 6 通过调控肝癌细胞的谱系可塑性（lineage plasticity），促进肝癌进展与耐药的机制，并初步报道
MicroRNA Detection in Bone Marrow Cells by LNA-FISH
for mature miRNAs are detected using an anti-DIG fluorescein isothiocyanate (FITC) conjugated antibody and the fluorescent signals visualised with a confocal microscope, which permits the spatial localisation of the miRNAs. Using LNA-FISH
Immunohistochemistry: Fluorescence Protocol 2.0
that have been harvested, fixed and permeabilized at the peak of cytokine production after in vitro stimulation with strong polyclonal activators such as phorbol 12-myristate 13 acetate/ionomycin, anti-CD3+ CD28 monoclonal antibody, LPS or bacterial superantigens
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