CDH1 mouse monoclonal antibody

gene_symbol：CDH1
predicted_size：94.8 kDa
Uniprot ID：P1283
description：CDH1 mouse monoclonal antibody,clone UMAB184
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
immunogen：The extracellular domain of human CDH1 (NP_004351) produced in human cells.
recommended_dilution：IHC 1:100~200
predicted_size：94.8 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：10k-ChIP, FC, IF, IHC, WB
reactivities：Human