产品英文名称: Recombinant Human NAD(P)H Dehydrogenase Quinone 1
英文简称: NQO1
中文名称: 重组人NAD(P)H脱氢酶, 醌1
背景资料: NQO1 belongs to the NAD(P)H dehydrogenase(quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 acts as an imperative part of cellular antioxidant defense by detoxifying quinines therefore preventing the formation of reactive oxygen species. It s人NAD(P)H脱氢酶, 醌1重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有294个氨基酸(1-274 a.a.),分子量为33kDa.该人NAD(P)H脱氢酶, 醌1重组蛋白的N末端融合了一个20个氨基酸的His标签,该蛋白最终由标准的色谱技术纯化出.ms that NQO1 serves as a quinone reductase relating to conjugation reactions of hydroquinons involved in detoxification pathways in addition to biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Altered NQO1 expression is s人NAD(P)H脱氢酶, 醌1重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有294个氨基酸(1-274 a.a.),分子量为33kDa.该人NAD(P)H脱氢酶, 醌1重组蛋白的N末端融合了一个20个氨基酸的His标签,该蛋白最终由标准的色谱技术纯化出.n in many tumors and also linked to Alzheimer’s disease. NQO1 gene mutations are linked to tardive dyskinesia which is an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer.