背景资料: HMOX2 cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently transferred to bilirubin by biliverdin reductase. Under physiological conditions, the activity of HMOX2 is highest in the spl人血红素氧合酶-2重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有264个氨基酸(1-264 a.a.),分子量为30.5kDa.该人血红素氧合酶-2重组蛋白最终由标准的色谱技术纯化出.n, where senescent erythrocytes are sequestrated and destroyed. HMOX2 participates in the production of carbon monoxide in the brain where it operates as a neurotransmitter. HMOX2 is an essential enzyme in heme catabolism and is involved in cellular response to oxidative stress.