重组人alpha-1微球蛋白

产品英文名称：
Recombinant Human Alpha-1 Antitrypsin， Active

英文简称:
SERPINA1， Active

中文名称:
重组人alpha-1抗胰蛋白酶，活性

背景资料:
SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase， plasmin， collagenase， thrombin， leucocytic proteases， trypsin， chymotrypsin， and plasminogen activator. Defects in SERPINA1 gene can cause emphysema or liver disease. Antral SERPINA1 expression is particularly induced by H. pylori infection. lung and prostate cancers have shown a significant increase in SERPINA1 serum levels compared with healthy controls though breast cancers did not show a significant change. SERPINA1 is an endogenous inhibitor of serine proteases and inhibits the catalytic domain of human recombinant matriptase in vitro. Rise in SERPINA1 occurs as an acute phase response to tissue necrosis and inflammation. mutations in SERPINA1 and SLC11A1 genes change the balance betwSERPINA1 Human Recombinant produced in rice is a single， non-glycosylated polypeptide chain containing 384 amino acids and having a molecular mass of 43.1 kDa. The SERPINA1 protein is purified by proprietary chromatographic techniques.n elastase produced by leukocytes during phagocytosis.

产品描述:
SERPINA1 Human Recombinant produced in rice is a single， non-glycosylated polypeptide chain containing 384 amino acids and having a molecular mass of 43.1 kDa. The SERPINA1 protein is purified by proprietary chromatographic techniques.
来源宿主:
水稻 （Oryza Sativa）中重组表达

序列:


溶解建议:
提供的重组人alpha-1抗胰蛋白酶，活性产品形式为冻干粉末.建议用无菌处理的18M-cm水溶解重组人alpha-1抗胰蛋白酶，活性，浓度不低于100ug/ml.后继实验过程中可根据实验要求进一步稀释.

保存建议：
重组人alpha-1抗胰蛋白酶，活性产品在室温保存3周，于-18°C以下长期保存.一旦溶解，于4°C保存2-7天.长期存储建议添加0.1%HSA或BSA载体蛋白.避免反复冻融
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。