重组人热激蛋白27

产品英文名称：
Recombinant Human Heat Shock 22 kDa Protein-8， His Tag

英文简称:
HSPB8 His

中文名称:
重组人27kDa热激蛋白家族成员8，His标签

背景资料:
HSPB8 is part of the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. HSPB8 is induced by estrogen in estrogen receptor-positive breast cancer cells. HSPB8 protein functions as a chaperone in association with BAG3， a stimulator of macroautophagy. HSPB8 participates in the regulation of cell proliferation， apoptosis， and carcinogenesis. Mutations in HSPB8 gene have bHSPB8 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 216 amino acids （1-196 a.a.） and having a molecular mass of 23.7kDa. The HSPB8 is fused to a 20 amino acid His Tag at N-terminus and purified by conventional chromatography.n related with di大肠杆菌中重组表达erent neuromuscular diseases， including Charcot-Marie-Tooth disease.

产品描述:
HSPB8 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 216 amino acids （1-196 a.a.） and having a molecular mass of 23.7kDa. The HSPB8 is fused to a 20 amino acid His Tag at N-terminus and purified by conventional chromatography.
来源宿主:
大肠杆菌中重组表达

序列:
MGSSHHHHHH SSGLVPRGSH MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT.

溶解建议:
Sterile Filtered colorless solution. The HSPB8 protein solution contains 20mM Tris-HCl pH-8， 100mM NaCl， and 10% glycerol.

保存建议：
HSPB8 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。