重组人RO-60/SS-A蛋白

产品英文名称：
Recombinant Human RO-52/SS-A

英文简称:
ROSS52

中文名称:
重组人RO-52/SS-A蛋白

背景资料:
TRIM21 is a member of the tripartite motif （TRIM） family. The TRIM motif includes thrRO-52 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain having a molecular mass of 52kDa. The RO-52 is purified by proprietary chromatographic techniques. zinc-binding domains， a RING， a B-box type 1 and a B-box type 2， and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein， which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells， and tissue specific di大肠杆菌中重组表达erences in Ro/SSA proteins were identified.

产品描述:
RO-52 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain having a molecular mass of 52kDa. The RO-52 is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGG GSVCAVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCA VHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKL QVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNF LVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRC HSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTC AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLG AQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWT IWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGS LIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY.

溶解建议:
Sterile Filtered clear solution. The protein solution contains 6M Urea， 500mM NaCl and 10mM Tris pH8.0.

保存建议：
Lyophilized RO-52 although stable at 4℃ for 3 weeks， should be stored desiccated below -18℃. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。