重组人非T细胞活化连接蛋白

产品英文名称：
Recombinant Human Neuroblastoma RAS Viral Oncogene Homolog

英文简称:
NRAS

中文名称:
重组人神经母细胞瘤RAS Viral 病毒原癌基因同系物

背景资料:
NRAS binds GDP/GTP and has intrinsic GTPase activity. NRAS is a membrane protein that shuttles betwNRAS Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 186 amino acids （1-186 a.a.） and having a molecular mass of 20.8kDa. The NRAS is purified by conventional chromatography.n the Golgi apparatus and the plasma membrane. This transport is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. NRAS is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this NRAS gene result in juvenile myelomonocytic leukemia.

产品描述:
NRAS Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 186 amino acids （1-186 a.a.） and having a molecular mass of 20.8kDa. The NRAS is purified by conventional chromatography.
来源宿主:
大肠杆菌中重组表达

序列:
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP FIETSAKTRQ GVEDAFYTLV REIRQYRMKK LNSSDDGTQG CMGLPC.

溶解建议:
Sterile Filtered colorless solution. The NRAS protein solution contains 20mM Tris-HCl pH-7.5， 100mM NaCl， and 10% glycerol.

保存建议：
NRAS although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。