重组人非肌肉肌球蛋白-II调控轻链

产品英文名称：
Recombinant Human Non-Metastatic Cells 1

英文简称:
NME1

中文名称:
重组人非转移性细胞1蛋白

背景资料:
NDK （Nucleoside diphosphate kinase） exists as a hexamer composed of ’A’ （encoded by NME1） and ’B’ （encoded by NME2） isoforms. NME1 is involved in cell proliferation， di大肠杆菌中重组表达erentiation and development， signal transduction， G protein-coupled receptor endocytosis， and gene expression. It also has tumor metastasis-suppressive capacity. NME1 has a key role in the synthesis of nucleoside triphosphates other than ATP. NME1 is essential for neural development including neural patterning and cell future determination. The NME1 gene is expressed in various tumor types where its levels have bNME1 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 152 amino acids （1-152 a.a.） and having a molecular mass of 17.1kDa. The NME1 is purified by proprietary chromatographic techniques.n alternatively linked to reduced or increased metastatic potential. Decrease in NME1 expression is notably connected to aMANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVESAEKEI GLWFHPEELV DYTSCAQNWI YE.ressive behavior in melanoma， breast， colon， and gastric carcinomas. In contrast， elevated levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas. Somatic mutations of the NME1 gene are found in neuroblastoma. Increased NME1 in neuroblastoma is linked to features of the disease that are associated with aMANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVESAEKEI GLWFHPEELV DYTSCAQNWI YE.ressive tumors.

产品描述:
NME1 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 152 amino acids （1-152 a.a.） and having a molecular mass of 17.1kDa. The NME1 is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVESAEKEI GLWFHPEELV DYTSCAQNWI YE.

溶解建议:
Sterile Filtered colorless solution. The NME1 solution contains 20mM Tris-HCl buffer （pH7.5）， 1mM DTT and 10% glycerol.

保存建议：
NME1 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。