重组人肌血球素，不含亚铁血红素

产品英文名称：
Human Myoglobin

英文简称:
Myoglobin

中文名称:
人肌红蛋白

背景资料:
Myoglobin is a member of the globin superfamily and can be found in skeletal and cardiac muscles. It is a haemoprotein that contributs to intracellular oxygen storage and transcellular facilitated di人心脏组织中提取纯化usion of oxygen. Myoglobin has a single-chain globular structure of 153 amino acids， containing a heme prosthetic group （iron-containing porphyrin） in the core around which the remaining apoprotein folds. Myoglobin has 8 alpha helices and a hydrophobic core. Myoglobin’s molecular weight is 16.7 kDa， and it is the primary oxygen-carrying pigment of muscle tissues. The binding of oxygen in myoglobin is di人心脏组织中提取纯化erent from the cooperative oxygen binding in hemoglobin， since positive collaboration is a property of multimeric/oligomeric proteins only. Instead， the binding of oxygen by myoglobin is uninfluenced by the oxygen pressure in the surrounding tissue. Myoglobin is frequently referred to as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve. Di人心脏组织中提取纯化erent organisms are able to hold their breaths longer due to high concentrations of myoglobin in their muscle cells. Myoglobin is responsible for the pigments that make meat red. The color of the meat is partly determined by the charge of the iron atom in myoglobin and the oxygen attached to it. Myoglobin is found in Type I muscle， Type II A and Type II B， but it is mostly dHuman Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa. Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex.med that myoglobin is not found in smooth muscle. Myoglobin is discharged from damaged muscle tissue （rhabdomyolysis）， which contains very high concentrations of myoglobin. Even though the released myoglobin is filtered by the kidneys， it is toxic to the renal tubular epithelium and thus may cause acute renal failure.

产品描述:
Human Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa. Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex.
来源宿主:
人心脏组织中提取纯化

序列:


溶解建议:
Sterile Filtered red solution. The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.2uM membrane.

保存建议：
Human Myoglobin should be stored at 2-8℃.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。