重组人增殖细胞核抗原，Sf9表达

产品英文名称：
Recombinant Human Calbindin-1

英文简称:
CALB1

中文名称:
重组人钙结合蛋白-1

背景资料:
Calbindin 1 （CALB1） is a calcium binding protein that is a member of the troponin C superfamily. CALB1 plays a vital role in calcium regulation （including calcium transport and uptake， calcification of bone and tCALB1 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 261 amino acids （1-261 a.a.） and having a molecular mass of 30kDa. The CALB1 is purified by proprietary chromatographic techniques.th） and calcium associated signaling in neurons and transiently in embryological development. CALB1 also has a role in protecting neurons from apoptotic cell death. CALB1 bu大肠杆菌中重组表达ers cytosolic calcium and may stimulate a membrane Ca2+-ATPase and a 3’，5’-cyclic nucleotide phosphodiesterase. The biological function of CALB1 sCALB1 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 261 amino acids （1-261 a.a.） and having a molecular mass of 30kDa. The CALB1 is purified by proprietary chromatographic techniques.ms to be tied to the redox state of its five cysteine residues. CALB1 has 4 active calcium-binding domains， and 2 modified domains that sCALB1 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 261 amino acids （1-261 a.a.） and having a molecular mass of 30kDa. The CALB1 is purified by proprietary chromatographic techniques.mingly have lost their calcium-binding ability. CALB1 is expressed in neural tissues. In the brain， the CALB1 synthesis is independent of vitamin-D-derived hormones. Disregulation of the CALB1 is associated with epilepsy， amyotrophic lateral sclerosis， Huntington’s disease. The neurons in brains of Huntington disease patients are calbindin-depleted.

产品描述:
CALB1 Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 261 amino acids （1-261 a.a.） and having a molecular mass of 30kDa. The CALB1 is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MAESHLQSSL ITASQFFEIW LHFDADGSGY LEGKELQNLI QELQQARKKA GLELSPEMKT FVDQYGQRDD GKIGIVELAH VLPTEENFLL LFRCQQLKSC EEFMKTWRKY DTDHSGFIET EELKNFLKDL LEKANKTVDD TKLAEYTDLM LKLFDSNNDG KLELTEMARL LPVQENFLLK FQGIKMCGKE FNKAFELYDQ DGNGYIDENE LDALLKDLCE KNKQDLDINN ITTYKKNIMA GGKLYRT DLALILCAGD N.

溶解建议:
Sterile Filtered colorless solution. The CALB1 protein solution contains 20mM Tris-HCl buffer （pH8.0）， 1mM DTT， 10% glycerol and 2mM EDTA.

保存建议：
CALB1 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。