重组人上皮有丝分裂原, His标签

产品英文名称：
Recombinant Human Fibroblast Growth Factor-23

英文简称:
FGF 23

中文名称:
重组人成纤维细胞生长因子-23

背景资料:
FGF-23 is a member of the fibroblast growth factor （FGF） family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development，cell growth，morphogenesis，tissue repair，tumor growth and invasion. FGF-23 inhibits renal tubular phosphate transport. The FGF-23 gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets （ADHR），an inherited phosphate wasting disorder. Abnormally high level expression of FGF-23 was found in oncogenic hypophosphatemic osteomalacia （OHO），a phenotypically similar disease caused by abnormal phosphate metabolism. FGF-23 mutations have also bFibroblast Growth Factor-23 Human Recombinant produced in E.Coli is a single，non-glycosylated polypeptide chain containing a total of 228 amino acids and having a molecular mass of 22.5kDa. The FGF-23 is and purified by chromatographic techniques.n shown to cause familial tumoral calcinosis with hyperphosphatemia.

产品描述:
Fibroblast Growth Factor-23 Human Recombinant produced in E.Coli is a single，non-glycosylated polypeptide chain containing a total of 228 amino acids and having a molecular mass of 22.5kDa. The FGF-23 is and purified by chromatographic techniques.
来源宿主:
大肠杆菌重组表达

序列:
MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSSDP LGVVRGGRVN THAGGTGPEG CRPFAKFI.

溶解建议:
提供的重组人成纤维细胞生长因子-23产品形式为冻干粉末.我们建议加无菌的18MΩ-cm水以配制工作储存液到不低于100ug/ml，后继实验过程中可根据实验要求进一步稀释.

保存建议：
人成纤维细胞生长因子-23产品在室温条件下可以保存3周，应该置于-18℃或更低温度下干燥保存.重新溶解后可置于4度保存2-7天，置于-18℃或更低温度下可保存更长时间.推荐添加载体蛋白 （0.1% HSA或BSA）以长期保存，请避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。