重组人激活素-A

产品英文名称：
Recombinant Human Protein Kinase C gamma

英文简称:
PKC-g

中文名称:
重组人蛋白激酶C-γ

背景资料:
Protein kinase C （PKC） is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters， a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has bPKC-g Human Recombinant produced in Sf9 is a glycosylated， polypeptide chain containing amino acids 2-676 and having a molecular mass of 80 KD. This protein is the full-length form of the protein with an amino terminal poly His-tag. PKC-g is purified by proprietary chromatographic techniques.n demonstrated that several neuronal functions， including long term potentiation （LTP） and long term depression （LTD）， specifically require this kinase. Knockout studies in mice also suest that this kinase may be involved in neuropathic pain development. Defects in this protein have bPKC-g Human Recombinant produced in Sf9 is a glycosylated， polypeptide chain containing amino acids 2-676 and having a molecular mass of 80 KD. This protein is the full-length form of the protein with an amino terminal poly His-tag. PKC-g is purified by proprietary chromatographic techniques.n associated with neurodegenerative disorder spinocerebellar ataxia-14 （SCA14）.

产品描述:
PKC-g Human Recombinant produced in Sf9 is a glycosylated， polypeptide chain containing amino acids 2-676 and having a molecular mass of 80 KD. This protein is the full-length form of the protein with an amino terminal poly His-tag. PKC-g is purified by proprietary chromatographic techniques.
来源宿主:
Sf9昆虫细胞中重组表达

序列:


溶解建议:
提供的人蛋白激酶C-γ（PKC-g）产品为过滤灭菌的透明溶液；其中0.1mg/ml人蛋白激酶C-γ（PKC-g）产品溶解于10mM Tris，pH 7.4，0.1M NaCl，20%甘油，1mM DTT，0.1mM EDTA，0.2mM PMSF，0.03% Brij-35溶液中.

保存建议：
人蛋白激酶C-γ（PKC-g）溶液可以在4℃冷藏保存2-4周；如果想延长保存时间，建议分装后置于-20℃冻存.请避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。