重组南美洲锥虫抗原1F8

产品英文名称：
Recombinant Human Fibroblast Growth Factor Receptor-3

英文简称:
FGFR3

中文名称:
重组人成纤维细胞生长因子受体-3

背景资料:
Fibroblast Growth Factors （FGFs） comprise a family of at least eightSoluble FGFR-3a （IIIc） Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric， glycosylated， Polypeptide chain and having a molecular mass of 190 kDa. The FGFR3 is purified by proprietary chromatographic techniques.n structurally realted proteins that are involved in a multitude of physiological and pathological cellular processes， including cell growth， di昆虫细胞中重组表达erentation， angiogenesis， wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors， FGFR-1to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGFR-1 and -2 results in receptors containing all thrSoluble FGFR-3a （IIIc） Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric， glycosylated， Polypeptide chain and having a molecular mass of 190 kDa. The FGFR3 is purified by proprietary chromatographic techniques. Ig domains， referred to as the alpha isoform， or only IgII and IgIII， referred to as the ? isoform. Only the alpha isoform has bSoluble FGFR-3a （IIIc） Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric， glycosylated， Polypeptide chain and having a molecular mass of 190 kDa. The FGFR3 is purified by proprietary chromatographic techniques.n identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3， involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons， generate FGF receptors with alternative IgIII domains （IIIb and IIIc）. A IIIa isoform which is a secreted FGF binding protein containing only the N-terminal half of the IgIII domain plus some intron sequences has also bSoluble FGFR-3a （IIIc） Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric， glycosylated， Polypeptide chain and having a molecular mass of 190 kDa. The FGFR3 is purified by proprietary chromatographic techniques.n reported for FGFR-1. Mutations in FGFR-1 to -3 have bSoluble FGFR-3a （IIIc） Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric， glycosylated， Polypeptide chain and having a molecular mass of 190 kDa. The FGFR3 is purified by proprietary chromatographic techniques.n found in patients with birth defects involving craniosynostosis.

产品描述:
Soluble FGFR-3a （IIIc） Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric， glycosylated， Polypeptide chain and having a molecular mass of 190 kDa. The FGFR3 is purified by proprietary chromatographic techniques.
来源宿主:
昆虫细胞中重组表达

序列:


溶解建议:
提供的人成纤维细胞生长因子受体-3（FGFR3）产品为过滤灭菌的白色冻干粉末；该冻干粉末是从含1mg/ml人成纤维细胞生长因子受体-3（FGFR3）的溶液（不含添加剂）中过滤灭菌并冻干产生的.我们建议加无菌的PBS以配制工作储存液到不低于100ug/ml，后继实验过程中可根据实验要求进一步稀释.

保存建议：
人成纤维细胞生长因子受体-3（FGFR3）冻干粉末在室温可保存3周，或置于-18℃冻存用于长期保存.重新溶解后可以在4℃冷藏保存至少2-7天以上；如果想延长保存时间，建议分装（加载体蛋白如0.1% HSA或 BSA）后置于-18℃冻存.请避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。