产品英文名称: Recombinant Mycobacterium Tuberculosis major secretory protein Antigen 85A
英文简称: Ag85A
中文名称: 重组结核分枝杆菌主要分泌蛋白抗原85A
背景资料: Antigen 85A is a member of the antigen 85 complex (Antigen 85A, B, C). The enzymes of the antigen 85 complex have mycolyltransferase activity and catalyze the synthesis of the very rich glycolipid of the mycobacterial cell wall, the cord factor (trehalose 6,6’-dimycolate, TDM). The cord factor is vital for the integrity of the mycobacterial cell wall and pathogenesis of the bacillus. TDM is synthesized from two molecules of trehalose-6’-monomycolate (TMM) by Antigen 85A.
产品描述: Recombinant Mycobacterium tuberculosis Ag85A (43-338 a.a) produced in Hi-5 cells is a single, glycosylated polypeptide chain having a molecular mass of 32.8kDa (305 a.a in total).Antigen 85A is fused to a His tag at C-terminus and purified by conventional chromatographic techniques.
来源宿主: 大肠杆菌中重组表达