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- 详细信息
- 文献和实验
- 技术资料
- 形态:
液体
- 保存条件:
4度
- 克隆性:
Monoclonal Antibody
- 标记物:
S/N
- 适应物种:
Human
- 宿主:
Mouse
- 应用范围:
C, IP, WB
- 浓度:
请参考说明书
- 靶点:
PI-3 KINASE p85 SUBUNIT BETA
- 抗体英文名:
MOUSE ANTI PI-3 KINASE p85 SUBUNIT BETA
- 抗体名:
MOUSE ANTI PI-3 KINASE p85 SUBUNIT BETA
- 规格:
2 ml
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文献和实验Evaluating the Therapeutic Potential of mTOR Inhibitors Using Mouse Genetics
effector of PI3K signaling, one of the most frequently activated pathways in cancer. In cells, mTOR is the catalytic core subunit of two distinct complexes, mTORC1 and mTORC2, which are defined by unique mTOR-interacting proteins and have unique functions
on the PI3K p85 regulatory subunit, or the adaptor proteins IRS1 and IRS2. IRS1 and IRS2 are phosphorylated by the activated receptor, generating docking sites for the SH2 domains of p85 and inducing proper assembly of the signalling complex. These SH2–
on the PI3K p85 regulatory subunit, or the adaptor proteins IRS1 and IRS2. IRS1 and IRS2 are phosphorylated by the activated receptor, generating docking sites for the SH2 domains of p85 and inducing proper assembly of the signalling complex. These SH2–
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