Recombinant Human A2M / CPAMD5 / Alpha-2-macroglobulin Protein (His Tag)
库存:
99
供应商:
北京义翘神州科技股份有限公司
规格:
50 µg
人 alpha-2-macroglobulin蛋白|alpha-2-macroglobulin protein|alpha-2-macroglobulin(Human, C-His)(产品说明)
蛋白名称:alpha-2-macroglobulin蛋白, alpha-2-macroglobulin protein
蛋白构建:A DNA sequence encoding the human A2M (NP_000005.2) (Met 1-Ala 1474) was expressed, fused with a polyhistidine tag at the C-terminus.
表达宿主:Baculovirus-Insect Cells
蛋白纯度:> 85 % as determined by SDS-PAGE
蛋白活性:Measured by its ability to trap trypsin. The trapped trypsin is no longer able to interact with protein substrates or inhibitors, but still able to cleave small peptide substrates or inhibitors.The IC50 value is <5 nM.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ser 24
蛋白分子量:The recombinant human A2M consists of 1461 amino acids and predicts a molecular mass of 164 kDa. The apparent molecular mass of rhA2M is approximately 160-170 kDa in SDS-PAGE under reducing conditions.
蛋白NP号:NP_000005.2
蛋白氨基酸序列:Met1-Ala1474
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
1, Klint, S; et al. Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis. mAbs, Pubmed: 37184136
2, N'Guessan, K; et al. Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. FEBS J., Pubmed: 31995266