小鼠 B7-1蛋白|B7-1 protein|B7-1(Mouse, C-human IgG1-Fc)(产品说明)
蛋白名称:B7-1蛋白, B7-1 protein
蛋白构建:A DNA sequence encoding the mouse CD80 (Q00609-1) extracellular domain (Met 1-Lys 245) was fused with the Fc region of human IgG1 at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:1. Measured by its binding ability in a functional ELISA.2. Immobilized human CTLA4 (cat: 11159-H08H) at 10 μg/mL (100 μl/well) can bind mouse CD80-Fc (cat: 50446-M02H), The EC50 of mouse CD80-Fc (cat: 50446-M02H) is 28 ng/mL.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Val 38
蛋白分子量:The recombinant mouse CD80 consists of 449 amino acids and has a predicted molecular mass of 50.7 kDa.
蛋白NP号:Q00609-1
蛋白氨基酸序列:Met1-Lys245
蛋白标签:C-human IgG1-Fc
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
1, Liu, M; et al. Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immunotherapy. Science translational medicine, Pubmed: 36857433