- ￥2480 - 13980
- Sino Biological
- 北京
- 13092-H08H
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Human Follistatin / FST (FS288) Protein (His Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
50 µg/500 µg
| 规格： | 50 µg | 产品价格： | ￥2480.0 |
|---|---|---|---|
| 规格： | 500 µg | 产品价格： | ￥13980.0 |
重组人 Follistatin / FST (FS288) 蛋白 (His标签)（产品说明）
蛋白名称：Human Follistatin / FST (FS288) Protein (His Tag)
蛋白构建：A DNA sequence encoding the human FST isoform FST288 (P19883-2) (Met 1-Asn 317) was fused with a polyhistidine tag at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 20-80 ng/mL in the presence of 10 ng/mL Recombinant Human Activin A.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gly 30
蛋白分子量：The secreted recombinant human FST (FS288) consists of 299 amino acids and has a predicted molecular mass of 33 kDa. As a result of glycosylation, rhFST (FS288) migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号：P19883-2
蛋白氨基酸序列：Met1-Asn317
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human Follistatin / FST (FS288) Protein (His Tag)
蛋白构建：A DNA sequence encoding the human FST isoform FST288 (P19883-2) (Met 1-Asn 317) was fused with a polyhistidine tag at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 20-80 ng/mL in the presence of 10 ng/mL Recombinant Human Activin A.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gly 30
蛋白分子量：The secreted recombinant human FST (FS288) consists of 299 amino acids and has a predicted molecular mass of 33 kDa. As a result of glycosylation, rhFST (FS288) migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号：P19883-2
蛋白氨基酸序列：Met1-Asn317
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验相关实验
内源性FSTL1 通过激活钠‐钾泵引起膜超极化调节痛觉信息传递
‐钾泵活性；然而，人体内是否存在钠‐钾泵的内源性的激动剂还不清楚。 近日，中科院上海生科院神经所张旭实验室通过对背根神经节（dorsal root ganglion，DRG）的研究，发现在 DRG 中有一种选择性高表达的蛋白——滤泡素抑制素样蛋白 1（Follistatin‐like 1，FSTL1）能通过清亮小泡运输至脊髓内的传入神经末端释放，并直接与传入神经末端突触前膜上的钠‐钾泵 α1 亚基相结合，增强钠‐钾泵活性，使细胞膜超极化，从而对传入神经末端的兴奋性突触传递起抑制
酶(RNA-inducedsilencingcomplex，Dicer)切割成21~26nt长的siRNA，通过siRNA指导形成RISC蛋白复合物(RNA-inducedsilencingcomplex)降解与siRNA序列互补的mRNA而引发RNA沉默。而miRNA途径中miRNA是含量丰富的不编码小RNA(21~24个核苷酸)，由Dicer酶切割内源性表达的短发夹结构RNA(hairpinRNA,hpRNA)形成。miRNA同样可以与蛋白因子形成RISC蛋白复合物，可以结合并切割特异的mRNA
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重组人 Follistatin / FST (FS288)蛋白 (His 标签)
￥2480 - 13980
