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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
天然和重组IL-17A
- 抗体英文名:
anti-human/monkey IL-17A mAb MT241, purified
- 规格:
250ug
产品名称:anti-human/monkey IL-17A mAb MT241, purified-anti-human/monkey IL-17A mAb MT241, purified
产品货号:3520M-3-250 产品规格:250ug 应用类型:ELISpot, ELISA
保存建议:anti-human/monkey IL-17A mAb MT241, purified-anti-human/monkey IL-17A mAb MT241, purified建议收到产品后2-8°C保存,有效期为18个月。
背景资料:Interleukin-17A (IL-17A, IL17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has been shown to also be produced by activated CD8+ T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection.
点击:anti-human/monkey IL-17A mAb MT241, purified-anti-human/monkey IL-17A mAb MT241, purified查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询Mabtech中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
Mabtech 公司是一家欧洲的集研究,开发,销售,技术支持为一体的高科技免疫生物技术公司。Mabtech公司始终专业致力于研发新的单克隆抗体,生产创新的免疫试剂和销售高品质的全配套的免疫试剂盒。公司核心业务是致力于优化发展酶联免疫斑点法技术 (ELISpot)、荧光免疫斑点法技术 (FluoroSpot) 和酶联免疫吸附试验技术 (ELISA) 等免疫学方法。作为Mabtech在中国的区域代理,艾美捷科技有限公司将为中国客户提供全面的Mabtech产品以及客户订制化服务。
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关键词:anti-human/monkey IL-17A mAb MT241, purified,anti-human/monkey IL-17A mAb MT241, purified, IL-17A mAb MT241
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文献和实验T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
with one of the positive control stimuli, i.e., CEF or anti-CD3 mAb (Step 13). Wells coated with anti-IL-2 coating buffer should contain only blue spots. Wells coated with anti-IFN- coating buffer should contain only red spots. i. Set sensitivity
Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
with one of the positive control stimuli, i.e., CEF or anti-CD3 mAb (Step 13). Wells coated with anti-IL-2 coating buffer should contain only blue spots. Wells coated with anti-IFN- coating buffer should contain only red spots. i. Set sensitivity
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