重组人趋化因子CXCL8(IL-8)

特别提示：包括重组人趋化因子CXCL8(IL-8)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人趋化因子CXCL8(IL-8)
英文名称：Recombinant Human C-X-C motif chemokine 8/Interleukin 8
产品货号：JN0323
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物表达系统制备，目的基因编码的Glu21-Ser99在C端含有His标签。

CXCL8/IL-8质量控制：＞95%(还原性SDS-PAGE)。

CXCL8/IL-8制剂：冻干品

CXCL8/IL-8保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL8/IL-8复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL8/IL-8：
Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.

除了重组人趋化因子CXCL8(IL-8),，我公司还供应以下相关产品：



名称：重组小鼠FGF1(酸性成纤维细胞生长因子)
货号：JN0253
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，表达蛋白包含序列(Phe16-Asp155)。

FGF-1质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)

FGF-1制剂：冻干品

FGF-1保存：

关于FGF-1：
FGF acidic is a 17 kDa nonglycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors.

名称：重组人Gankyrin蛋白(癌性锚蛋白重复序列)
货号：JN1952
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Gly226表达纯化得来。

Gankyrin质量控制：＞95%(还原性SDS-PAGE)

Gankyrin制剂：液体

Gankyrin保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Gankyrin：
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.

名称：重组人肌动蛋白结合蛋白2(Profilin-2)(PFN2)
货号：JN1043
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Phe140表达纯化得来。

PFN2质量控制：＞95%(还原性SDS-PAGE)

PFN2制剂：冻干品

PFN2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PFN2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PFN2：
Profilin-II (PFN2) is ubiquitous protein which belongs to the profilin family. PFN2 binds to actin, thenaffects the structure of the cytoskeleton. At high concentrations, profiling prevents the polymerization of actin, while increases that at low concentrations. PFN2 is a ubiquitous actin monomer-binding protein. It regulates actin polymerization in response to extra cellular signals. PFN2 binds to PIP2; it inhibits the formation of IP3 and DG.

名称：重组人Carboxypeptidase A1(羧肽酶A1)(CPA1)
货号：JN1732
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Lys17-Tyr419在C端含有His标签。

Carboxypeptidase A1/CPA1质量控制：＞95%(还原性SDS-PAGE)

Carboxypeptidase A1/CPA1制剂：液体

Carboxypeptidase A1/CPA1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Carboxypeptidase A1/CPA1：
Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E.