Product overview
Description Anti-GLI1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human GLI1
Reactivity Human, Mouse
Content 0.9 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GLI1
Full name GLI family zinc finger 1
Synonyms GLI
Swissprot P08151
Target Background
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.