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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
单克隆
- 保质期:
12个月
- 抗体英文名:
Anti-TG antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.8 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC262350
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-TG rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human TG
Reactivity Human
Content 0.8 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol TG
Full name thyroglobulin
Synonyms TGN; AITD3
Swissprot P01266
Target Background
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Anti-TG antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 30-150
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